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Azatadina [INN-Spanish] en es it fr

Azatadina [INN-Spanish] Brand names, Azatadina [INN-Spanish] Analogs

Azatadina [INN-Spanish] Brand Names Mixture

  • Actinac Pwr (Allantoin + Butoxyethyl Nicotinate + Chloramphenicol + Hydrocortisone Acetate + Sulfur)
  • Actinac Pws (Allantoin + Butoxyethyl Nicotinate + Chloramphenicol + Hydrocortisone Acetate + Sulfur)
  • Calmurid Hc Crm (Hydrocortisone + Urea)
  • Cortisporin (Bacitracin Zinc + Hydrocortisone + Neomycin Sulfate + Polymyxin B Sulfate)
  • Eye and Wound Powder (Chlorhexidine Hydrochloride + Hydrocortisone Acetate + Penicillin G Procaine + Sulfathiazole)
  • Forte Topical Suspension (Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Neomycin (Neomycin Sulfate) + Penicillin G Procaine + Polymyxin B Sulfate)
  • Neo-Cortef Eye Ear Dps (Hydrocortisone Acetate + Neomycin Sulfate)
  • Neo-Cortef Eye Ear Drops Sterile Suspension (Hydrocortisone Acetate + Neomycin Sulfate)
  • Neo-Cortef Eye Ear Ont (Hydrocortisone Acetate + Neomycin Sulfate)
  • Ophthocort Ont (Chloramphenicol + Hydrocortisone Acetate + Polymyxin B (Polymyxin B Sulfate))
  • Otizol Hc Liq (Hydrocortisone (Hydrocortisone Acetate) + Lidocaine (Lidocaine Hydrochloride) + Neomycin (Neomycin Sulfate))
  • Proctosedyl Ointment (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosedyl Sup (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosedyl Suppositories (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosone Ont (Dibucaine Hydrochloride + Esculin + Hydrocortisone Acetate + Neomycin Sulfate)
  • Proctosone Sup (Dibucaine Hydrochloride + Esculin + Hydrocortisone Acetate + Neomycin Sulfate)
  • Sopamycetin/Hc Ointment (Chloramphenicol + Hydrocortisone Acetate)
  • Sopamycetin/Hc Ont (Chloramphenicol + Hydrocortisone Acetate)
  • Sopamycetin/Hc Susp (Chloramphenicol + Hydrocortisone Acetate)
  • Ti-U-Lac Hc Lotion (Hydrocortisone + Urea)
  • Vioform + Hydrocortisone (Clioquinol + Hydrocortisone)
  • Vioform Hydrocortisone Cream (Clioquinol + Hydrocortisone)
  • Vioform Hydrocortisone Mild (Clioquinol + Hydrocortisone)
  • Vosol Hc (Acetic Acid + Benzethonium Chloride + Hydrocortisone + Propylene Glycol Diacetate)

Azatadina [INN-Spanish] Chemical_Formula

C20H22N2

Azatadina [INN-Spanish] RX_link

http://www.rxlist.com/cgi/generic3/azatpseud.htm

Azatadina [INN-Spanish] fda sheet

Azatadina [INN-Spanish] msds (material safety sheet)

Azatadina [INN-Spanish] Synthesis Reference

No information avaliable

Azatadina [INN-Spanish] Molecular Weight

290.402 g/mol

Azatadina [INN-Spanish] Melting Point

No information avaliable

Azatadina [INN-Spanish] H2O Solubility

Very soluble

Azatadina [INN-Spanish] State

Solid

Azatadina [INN-Spanish] LogP

2.927

Azatadina [INN-Spanish] Dosage Forms

Tablet

Azatadina [INN-Spanish] Indication

For the relief of the symptoms of upper respiratory mucosal congestion in perennial and allergic rhinitis, and for the relief of nasal congestion and eustachian t.b. congestion.

Azatadina [INN-Spanish] Pharmacology

Azatadine is an antihistamine, related to cyproheptadine, with anti-serotonin, anticholinergic (drying), and sedative effects. Azatadine is in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, azatadine is not used clinically as an anti-psychotic. Antihistamines antagonize the vasodilator effect of endogenously released histamine, especially in small vessels, and mitigate the effect of histamine which results in increased capillary permeability and edema formation. As consequences of these actions, antihistamines antagonize the physiological manifestations of histamine release in the nose following antigen-antibody interaction, such as congestion related to vascular engorgement, mucosal edema, and profuse, watery secretion, and irritation and sneezing resulting from histamine action on afferent nerve terminals.

Azatadina [INN-Spanish] Absorption

Well absorbed after oral administration.

Azatadina [INN-Spanish] side effects and Toxicity

The oral LD50 in mature rats and mice was greater than 1700 mg/kg and 600 mg/kg, respectively. Symptoms of overdose include clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia.

Azatadina [INN-Spanish] Patient Information

Azatadina [INN-Spanish] Organisms Affected

Humans and other mammals